My apologies, I had mixed up the color spaces output with input. The AV.io 4k can only output in Color spaces YUY2 (4:2:2), NV12, YV12, and I420 (4:2:0). However, it is only compatible with 8-bit color, so it’s possible that the Stryker is outputting 10-bit color which could certainly cause issues.
Another possibility, though I’d be surprised, is that the Stryker is encrypting the signal with HDCP. The Stryker manual doesn’t mention this, but it also says certain options and features are not covered by the manual and to learn about them one needs to contact a Stryker representative.
The variables I was referring to were things like the cable, the operating system on the PC, the software running on it, basically anything that is involved in the passing of video from the Stryker to the PC through the AV.io 4k. So, establishing that the AV.io 4k was functioning correctly was a priority before trying anything else.
Based on what you’ve told me so far though, it seems as though you might need to contact Stryker at this point to determine more details about the video output, specifically the bit depth of the video and HDCP encryption. If the AV.io 4k is working correctly with other sources, and the Stryker is correctly outputting over that HDMI port to a monitor then the issue likely lies in how the Stryker is outputting that video and only Stryker will be able to tell you that I’m afraid. I hope that this helps!